Cholesterol Lie Q & A

Dear Dr. Jonny,

Following your suggestion, I just finished reading "The Great Cholesterol Lie"! What an eye-opener.

But I recently read in the mainstream media about a study called the JUPITER Study that showed the benefit of statin drugs even for people with normal cholesterol! How can this be?

Well, I can certainly see why my reader was confused. So let's try to sort it out.

In the JUPITER study, people with normal cholesterol were given statin drugs. But these people didn't just have normal cholesterol- they also had elevated levels of a blood protein called C-reactive Protein (CRP).

When this group of people took statin drugs (specifically Crestor), their risk factors did indeed improve.

The question is, "Why?"

Here's the answer- and it's not nearly as confusing as the results might seem at first.

Statin drugs are mildly anti-inflammatory. I believe- and I'm quite sure Dr. Lundell would agree with me- that any good that statin drugs do is solely because of their ability to reduce inflammation. In the JUPITER Study, statins lowered CRP, which is- guess what- a measure of systemic inflammation!

And here's what backfired for the pharmaceutical company. This study confirmed the fact that cholesterol is largely irrelevant. The patients in the JUPITER Study were at risk not because their cholesterol was high (it wasn't) but because they had high levels of inflammation.

The statin drug lowered their inflammation, and any lowering of inflammation improves risk factors for heart disease, not to mention overall health. Let's not forget those nasty side effects of painful muscle cramping and recent studies that show extreme cognitive dysfunction from statins.

Wouldn't an aspirin be better? And better yet, Omega-3?

Statins are the "Frankenstein" medication of our time. And Dr. Lundell exposes the reasons why in his excellent book.

The bottom line is that Inflammation is a very, very serious thing—it's a silent killer.

Cholesterol is not. My advice? Take Omega-3 fish oil, the most anti-inflammatory compound on the planet and one that has exactly zero side effects. With fish oil available, why in the world would someone choose a statin as their anti-inflammatory drug of choice?

The simple steps to begin healing your heart outlined in Dr. Lundell's book, "The Great Cholesterol Lie" will absolutely astonish you.

Go here now and silence that deadly killer - inflammation.

25 Year Heart Surgeon Reveals The Statin Scam

Guest article by Dr. Dwight Lundell:

Television ads featuring artificial heart inventor Dr. Robert Jarvik (who never practiced medicine) claims that Lipitor will lower heart attack risk by 36%.

Now, who wouldn't want that? Let's look at the fine print...

"in a large clinical study 3% of people taking a placebo had a heart attack and 2% of those taking Lipitor had a heart attack."

Let's do the math...

• For every 100 people in the trial that lasted 3 l/2 years, 3 people on the placebo and 2 people on Lipitor had heart attacks. That is one less heart attack for every 100 people.
• In other words, 100 people had to take Lipitor for 3 l/2 years
• to prevent one heart attack.
• What this really means is, 99 out of 100 people taking Lipitor received no benefit.

There is a little known statistic, "Number Needed To Treat," (NNT) defined as the number of patients who need to be treated in order to prevent one bad outcome. In the case of Lipitor, 100 patients needed to be treated for 3 l/2 years to possibly eliminate one heart attack.

Let's compare that number to today's antibiotic treatment to eradicate ulcer causing H. pylori stomach bacteria. The Number Needed To Treat H. pylori is 1:1. That means if you give the antibiotic to 11 people, 10 will be cured.

Several recent scientific papers peg the NNT for statin medications at 250. That means 249 of 250 would receive no benefit.

Dr. Jerome R. Hoffman, Professor of Clinical Medicine at UCLA asks:

"What if you put 250 people in a room and told them they would have to pay over $1,000 per year for a medicine they must take every day that might give them diarrhea and muscle pain and that 249 of those people would get no benefit, how many would take that?"

Very, very few.

Drug companies have a responsibility to their shareholders to make a profit. We need drug companies to develop new medicines; however, when they grossly overstate benefits and spend enormous dollars influencing physicians, it leads to potential corruption.

The National Cholesterol Education Program (NCEP) 2004 guidelines lowered the targets for cholesterol treatment and recommended more Americans take statins. The panel that issued the guidelines was comprised of 9 experts, 8 of which had ties to the drug industry.

Physicians who speak out take great risks as medicine and government agencies do not like criticism. For example, Dr. Henry C. Barry of the Michigan State University College of Medicine recently stated, "The NCEP guideline and process went awry."

Dr. Barry and 34 other experts sent a petition of protest to the National Institutes of Health saying the evidence was weak and the panel biased because of its ties to the drug industry. Dr. Rodney A. Hayward, Professor of Internal Medicine at the University of Michigan Medical school said, "current evidence supports ignoring LDL cholesterol altogether."

In response to these statements The National Cholesterol Education Program stated strongly, "Dr. Hayward should be held accountable in a court of law for doing things to kill people."

We might expect this kind of harsh response from zealots and extremists but not from government agencies or scientists. If we spent just a fraction of the money we now do on cholesterol testing, cholesterol lowering drugs and doctors visits, on educating people about proper diet, exercise and weight loss, we'd be far healthier.

Dr. Lundell's New Book Backs What I've Been Saying About Cholesterol for Years!

The Great Cholesterol Lie Why Everything You Learned About Cholesterol Is A Lie, How It Began in 1948 And Why It Continues. Why Statin Medications Will Not Reduce Your Risk Of Heart Disease, And What Will. Extraordinary Simple Steps That Prevent And Reverse Heart Disease Without Medication. Learn More

The Truth About the Recent Cholesterol Drug Study

Last week, the results of a new study on a cholesterol-lowering drug were released generating a ton of press attention. The study (the JUPITER study) made the front page of the NY Times, was featured on just about every television news show, and generally created a lot of buzz. Even if you weren't paying too much attention- and it was hard not to- you might have heard that the study showed that a cholesterol-lowering medication (Crestor) lowered the risk for heart disease by over 40% in people who did not have high cholesterol in the first place!

The Wall Street Journal was practically salivating in its predictions. "The findings could substantially broaden the market for statins, the world's best-selling class of medicines", they panted. "Morgan Stanley analysts predicted Crestor revenue could rise to as much as 8 billion and 18% of the global statin market in 2014".

OK let's take a look at what actually happened before we start putting statins in the water supply.

Approximately 17,000 participants were enrolled in the study, all at "prime heart attack age" (over 50 for men, over 60 for women). But none had either high cholesterol levels nor evidence of serious heart disease. By all traditional measures, they were a healthy men and women.

What they did have was elevated inflammation.

We know this because the researchers measured their blood levels for CRP (C-Reactive Protein) an excellent marker for inflammation in the body. For years and years I- and many other nutritionists and doctors- have been warning that inflammation is the real danger for heart disease and that cholesterol is a red herring. Inflammation is the silent killer. Inflammation is what we should be paying attention to. C-Reactive Protein is an important measure to know, even though most docs have scoffed at it and told us it's not that important. (Besides, they were too busy focusing on cholesterol.)

For years I've also been saying that any benefit that might be had by taking statin drugs has nothing to do with lowering cholesterol. But statin drugs have an interesting little "side effect": they happen to lower inflammation.

So here's this study when people with completely normal cholesterol (but elevated inflammation) benefit from a statin drug. Think they'd figure out that maybe cholesterol wasn't the issue in the first place?

Oh no. What you'll probably see is a movement to lower the "normal" cholesterol levels even further down so that even more people can be put on these drugs.

Which, by the way, are far from perfectly safe. Though the mainstream establishment downplays their side effects, most knowledgeable clinicians will tell you that side effects like muscle pain and fatigue are far more common than widely believed and that they see these side effects in about 15% of patients. And the drug costs $3.50 a day, if you care.

So what we have here is a study that showed a very very modest reduction in risk for heart disease, using a drug that accomplished that not by lowering cholesterol but by lowering inflammation. The benefit of the drug-- such as it was (and it was modest to say the least)--- clearly had nothing to do whatsoever with lowering cholesterol.

By the way, how can I say that the benefit was modest when it was reported as a whopping 44% reduction in risk?

Simple. Because the percentages don't tell the whole story.

The real numbers were as follows: In the non-treated group, about 14 in 1000 developed cardiovascular disease (in other words 1.4 percent of the group). In the treated group, only 8 in 1000 developed cardiovascular disease (.8 percent). Tiny numbers- but reducing 14 to 8 does produce a "44% reduction" (just as reducing 3-in-a-million to 2-in-a-million produces a 33% reduction!)

Inflammation truly is an important health issue, and anything that reduces inflammation should be paid attention to. The sad part of all this is that there are so many ways to reduce inflammation naturally without drugs. Fish oil is one of the most anti-inflammatory substances on the plant. So are the myriad of natural anti-inflammatories (like the quercetin found in apples and onions, and the hundreds of other flavonoids in the plant kingdom).

But of course none of those are 20 billion dollar-a-year businesses.